1451 - 1508 (57 years)
| Francis Stewart | |
| B: | Abt 1563 |
| Scotland | |
| D: | Abt 1612 |
| Napoli, Campania, Italy | |
| Margaret Douglas | |
| B: | 1558 |
| Cockburnspath, Berwickshire, Scotland | |
| M: | Dec 1577 |
| D: | 1640 |
| Buccleuch, Scotland | |
| Lady Jean Hepburn | |
| B: | 1542 |
| Crichton Castle, Midlothian, Scotland | |
| D: | 27 Jul 1599 |
| Girnigo Castle, Caithness, Scotland | |
| John Stewart | |
| B: | 1 May 1531 |
| Edinburgh, Midlothian, Lothian, Scotland | |
| D: | 1 Nov 1563 |
| Inverness, Scotland | |
| Patrick III Hepburn | |
| B: | 1512 |
| Bothwell, Lanarkshire, Strathclyde, Scotland | |
| D: | 9 Sep 1556 |
| Dumfries, Dumfriesshire, Scotland | |
| Lady Agnes Sinclair | |
| B: | 1509 |
| Newburgh, Foveran, Aberdeenshire, England | |
| M: | 1533 |
| Bothwell, Midlothian, Scotland | |
| D: | 21 Mar 1572 |
| Bothwell, Lanarkshire, Scotland | |
| Sir Adam Hepburn | |
| B: | Apr 1492 |
| Bothwell, Lanarkshire, Scotland | |
| D: | 20 Aug 1514 |
| Branxton, Northumberland, England | |
| Isabel Stewart | |
| B: | 1472 |
| Traquier, Peebleshire, Scotland | |
| M: | 28 Aug 1511 |
| Scotland | |
| D: | 20 Feb 1557 |
| Edinburgh, Midlothian, Scotland | |
| Patrick Hepburn | |
| B: | 10 Jul 1451 |
| Bothwell, Lanarkshire, Scotland | |
| D: | 18 Oct 1508 |
| Stirling, Central, Scotland | |
| Janet Douglas | |
| B: | 1468 |
| Aberdeenshire, Grampian, Scotland | |
| D: | Scotland |
